RESUMO
Complex anthropometric and laboratory investigation of 30 healthy men produced evidence that body mass index and the lipoperoxidation product contents in blood sera may be regarded as associated indirect markers of neutrophiles' functional status and immunoglobulinemia.
Assuntos
Índice de Massa Corporal , Imunoglobulinas/sangue , Peróxidos Lipídicos/sangue , Neutrófilos/fisiologia , Adulto , Biomarcadores/sangue , Humanos , Imunoglobulinas/fisiologia , Masculino , Pessoa de Meia-Idade , Fagocitose/fisiologiaRESUMO
Study of relationship between the content of lipid peroxidation (LPO) products in the blood of patients with benign prostatic hyperplasia (BPH) and resistance to infectious inflammatory complications (IIC) of transurethral electroresection of the prostate showed that decreased content of circulating lipoperoxides promoted the development of postoperative IIC. Before the operation blood levels of LPO products were increased in BPH patients who did not develop IIC postoperation in comparison with normal controls. Three intravenous injections of ascorbic acid in a single dose of 1000 mg after transurethral electroresection of the prostate led to an increase in the blood level of LPO products and promoted a decrease in the incidence of postoperative IIC.
Assuntos
Infecções Bacterianas/diagnóstico , Inflamação/diagnóstico , Peroxidação de Lipídeos , Complicações Pós-Operatórias/diagnóstico , Hiperplasia Prostática/cirurgia , Ressecção Transuretral da Próstata/efeitos adversos , Antioxidantes/administração & dosagem , Ácido Ascórbico/administração & dosagem , Infecções Bacterianas/sangue , Infecções Bacterianas/prevenção & controle , Biomarcadores , Humanos , Inflamação/sangue , Inflamação/prevenção & controle , Injeções Intravenosas , Masculino , Complicações Pós-Operatórias/sangue , Complicações Pós-Operatórias/prevenção & controleRESUMO
Lipid peroxidation products and ceruloplasmin in the serum were measured in 78 patients with benign prostatic hyperplasia (BPH) in uncomplicated or complicated period after transurethral resection of the prostate (TUR) and before it. In uncomplicated period, a short rise in lipid peroxidation activity and lowering of ceruloplasmin concentrations were followed by normalisation by day 6. In the complicated postoperative period by day 6 these indices were higher. The authors propose that these indices are used in assessment of antioxidants efficacy after TUR for BPH.